This animation provides an overview of genetic changes or cellular mutations in moles of the skin which can help determine the best melanoma treatments for each patient. A genetic mutation in these cells due to excess sunlight, or family inherited genes results in increased risk for the development of melanoma. Melanoma mutations promote cancer by helping cells stay alive, grow, and divide; they occur in high levels in tumor cells. A pigmented lesion assay (PLA) adhesion patch test can help diagnose melanoma at a very early stage. It is important to talk with your doctor about whether genetic testing for melanoma risk is right for you.
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This educational activity has been developed by the Melanoma Research Foundation (MRF), and Mechanisms in Medicine Inc.
This activity is supported by independent educational grants from Bristol-Myers Squibb, Foundation Medicine, Genentech, Iovance Biotherapeutics, Merck, Natera, and Novartis.
This website is part of the Animated Patient™ series developed by Mechanisms in Medicine Inc., to provide highly visual formats of learning for patients to improve their understanding, make informed decisions, and partner with their healthcare professionals for optimal outcomes.